Calcium regulation of ciliary beat frequency in human respiratory epithelium in vitro.

The effect of drugs and other compounds on the ciliary beat frequency of human respiratory epithelium.

BACKGROUND Cilia in the human respiratory tract play a critical role in clearing mucus and debris from the airways. Their function can be affected by a number of drugs or other substances, many of which alter ciliary beat frequency (CBF). This has implications for diseases of the respiratory tract and nasal drug delivery. This article is a systematic review of the literature that examines 229 s...

Effect of Cilia Beat Frequency on Muco-ciliary Clearance

Background: The airway surface liquid (ASL), which is a ï‌‚uid layer coating the interior epithelial surface of the bronchi and bronchiolesis, plays an important defensive role against foreign particles and chemicals entering lungs.Objective: Numerical investigation has been employed to solve two-layer model consisting of mucus layer as a viscoelastic fluid and periciliary liquid layer as a New...

Influence of Neopterin on Ciliary Beat Frequency of Human Nasal Epithelial Cells in vitro

Acute infectious diseases of the respiratory tract are regularly associated with increased concentrations of neopterin in serum and/or urine. Most likely, the pteridine compound is not only a marker of an activated cellular immune system but may exert distinct biochemical functions in the process of infections as well. In response to viral contact, macrophages located in the nasal mucosa may re...

Variability in ciliary beat frequency in bronchiectasis.

Ciliary beat frequency in human bronchi and bronchioles.

STUDY OBJECTIVE This study aimed to determine the differences between ciliary beat frequencies of respiratory ciliated cells from peripheral bronchioles and from proximal bronchi in humans. DESIGN Measurements were made from resected lungs. Ciliated cells were harvested by brushing the mucosa of each site immediately after surgery. Brushings with a cytology brush were performed on normal area...